For both men and women, getting testosterone levels to optimal is my strongest weapon against fatigue. In fact, it is my best quality of life intervention (perhaps diet a close competitor in some patients). Not only does It greatly improve energy in nearly all patients, it also is a great mood elevator. I see many patients that have gone the traditional medicine route that have been prescribed Prozac or other anti-depressants, when the rout issue is testosterone deficiency. The grump old man syndrome is predominately testosterone deficiency.  Many patients can go off anti-depressants when the problems remedied. Sleep disturbance is extremely common, and it is also improved with testosterone replacement. If your quality of life is low on energy, mood and sleep, then you should get your levels checked by an expert that understands optimal levels. WARNING – optimal levels may be ABOVE the reported “normal”